研究業績 Publications

2005年

  • "Charge separation in a nonfluorescent donor-acceptor dyad derived from boron dipyrromethene dye, leading to photocurrent generation" Hattori, S., Ohkubo, K., Urano, Y., Sunahara, H., Nagano, T., Wada, Y.,Tkachenko, N.V., Lemmetyinen, H., Fukuzumi, S. J. Phys. Chem. B, 109, 15368 -15375 (2005).
  • "Investigation of the origin of ephedrine and methamphetamine by stable isotope ratio mass spectrometry: a Japanese experience" Yukiko Makiko, Yasuteru Urano and Tetsuo Nagano, Bulletin on Narcotics,LVll, 63-78 (2005).
  • "Evidence for pH Dependent Zn2+ Influx in K562 Erythroleukemia Cells: Studies Using ZnAF-2F Fluorescence and 65Zn2+ Uptake" Robert A. Colvin, Charles P. Fontaine, Dustin Thomas, Tomoya Hirano, Tetsuo Nagano and Kazuya Kikuchi, Arch. Biochem. Biophys., 442, 222-228 (2005).
  • "Organization of Supramolecular Assemblies of Fullerene, Porphyrin and Fluorescein Dye Derivatives on TiO2 Nanoparticles for Light Energy Conversion" Taku Hasobe, Shigeki Hattori, Prashant V. Kamat, Yasuteru Urano, Naoki Umezawa, Tetsuo Nagano and Shunichi Fukuzumi, Chemical Physics, 319, 243-252 (2005).
  • "The Detection and Quantification of Highly Reactive Oxygen Species Using the Novel HPF Fluorescence Probe in a Rat Model of Focal Cerebral Ischemia " Shinichiro Tomizawa, Hideaki Imai, Shota Tsukada, Tatsuya Simizu, Fumiaki Honda, Mitsunobu Nakamura, Tetsuo Nagano, Yasuteru Urano, Yuki Matsuoka, Noboru Fukasaku and Nobuhito Saito, Neuroscience Research, 53, 304-313 (2005).
  • "Highly Efficient and Photostable Photosensitizer Based on BODIPY Chromophore" Takatoshi Yogo, Yasuteru Urano, Yukiko Ishitsuka, Fumio Maniwa and Tetsuo Nagano, J. Am. Chem. Soc., 127, 12162-12163 (2005).
  • "Extension of the Application Range of Fluorescein: A Novel Fluorescein-based Probe for Western Blot Analysis" Mako Kamiya, Yasuteru Urano, Nobuyoshi Ebata, Masami Yamamoto, Jyunichi Kosuge and Tetsuo Nagano, Angewandte Chemie Int. Ed., 44, 5439- 5441 (2005).
  • "Selective Zinc Sensor Molecules with Various Affinities for Zn2+, Revealing Dynamics and Regional Distribution of Synaptically Released Zn2+ in Hippocampal Slices" Kensuke Komatsu, Kazuya Kikuchi, Hirotatsu Kojima, Yasuteru Urano and Tetsuo Nagano, J. Am. Chem. Soc., 127, 10197-10204 (2005).
  • "Enhanced Excitability of Hippocampal Mossy Fibers and CA3 Neurons under Dietary Zinc Deficiency" Atsushi Takeda, Kohei Yamada, Akira Minami, Tetsuo Nagano and Naoto Oku, Epilepsy Research, 63, 77-84 (2005).
  • "Inhibition of Autotaxin by Lysophosphatidic Acid and Sphingosine-1-phosphate" Laurens A. van Meeteren, Paula Ruurs, Evangelos Christodoulou, James W. Goding, Hideo Takakusa, Kazuya Kikuchi, Anastassis Perrakis, Tetsuo Nagano and Wouter H. Moolenaar, J. Biol. Chem.,  280, 21155-21161 (2005).
  • "Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs" Eita Sasaki, Hirotatsu Kojima, Hiroaki Nishimatsu, Yasuteru Urano, Kazuya Kikuchi, Yasunobu Hirata and Tetsuo Nagano, J. Am. Chem. Soc.,127, 3684-3685 (2005).
  • "Evolution of Fluorescein as a Platform for Finely Tunable Fluorescence Probes" Yasuteru Urano, Mako Kamiya, Kojiro Kanda, Tasuku Ueno, Kenzo Hirose and Tetsuo Nagano, J. Am. Chem. Soc.,127, 4888-4894 (2005).
  • "Design and Synthesis of Zinc-Selective Chelators for Extracellular Applications" Eri Kawabata, Kazuya Kikuchi, Yasuteru Urano, Hirotatsu Kojima, Akira Odani and Tetsuo Nagano, J. Am. Chem. Soc., 127, 818-819 (2005).
  • "Amyloid Induces Neuronal Cell Death through ROS-Mediated ASK1 Activation" Hisae Kadowaki, Hideki Nishitoh, Fumihiko Urano, Chiharu Sadamitsu, Atsushi Matsuzawa, Kohsuke Takeda, Hiroshi Masutani, Junji Yodoi, Yasuteru Urano, Tetsuo Nagano and Hidenori Ichijo, Cell Death and Differentiation,  12, 19-24 (2005).
  • "バイオイメージングとケミカルバイオロジー"　長野哲雄、浦野泰照、神谷真子、細胞工学、24(11)、1187-1191 (2005).
  • "活性酸素種・窒素種の生細胞プローブ"　浦野泰照、長野哲雄、アレルギー・免疫、12、745-751 (2005).
  • "新規機能性蛍光プローブの論理的開発"　浦野泰照、細胞、37(9)、38-42 （2005).
  • "蛍光法による生細胞からの活性酸素種・窒素種の検出"　浦野泰照、長野哲雄、酸化ストレスマーカー、二木鋭雄・野口範子・内田浩二編、17-22（2005).
  • "生細胞系での活性酸素種・窒素種の螢光イメージング"浦野泰照、長野哲雄、別冊医学のあゆみ　レドックスーストレス防御の医学ー、淀井淳司・松尾禎之編集、157-163(2005).
  • "レーザー分子機能不活性化を用いた膜インターフェイ スの機能解析"菊地和也、廣瀬謙造、飯野正光、長野哲雄、蛋白質核酸酵素、2005年8月号増刊号、 Vol. 50, No. 10, 1388-1394 (2005).

ページトップへ戻る

2004年

  • "Electronic Effects on Enantioselectivity in the Epoxidation Catalyzed by D4-Symmetric Chiral Porphyrins" Hiroshi Nakagawa, Yoshihisa Sei, Kentaro Yamaguchi, Tetsuo Nagano and Tsunehiko Higuchi, Tetrahedron: Asymmetry, 15, 3861-3867 (2004).
  • "Zinc Fluorescent Probes for Biological Applications" Tomoya Hirano, Kazuya Kikuchi and Tetsuo Nagano, Reviews in Fluorescence, 2004, 55-73 (2004).
  • "Enhanced Energy and Quantum Efficiencies of a Nanocrystalline Photoelectrochemical Cell Sensitized with a Donor-Acceptor Dyad Derived from Fluorescein"Shigeki Hattori, Taku Hasobe, Kei Ohkubo, Yasuteru Urano, Naoki Umezawa, Tetsuo Nagano, Yuji Wada, Shozo Yanagida and Shunichi Fukuzumi, J. Phys. Chem. B, 108, 15200-15205 (2004).
  • "Catalytic and Asymmetric Epoxidation by Novel D4-Symmetric Chiral Porphyrin Derived from C2-Symmetric Diols" Hiroshi Nakagawa, Yoshihisa Sei, Kentaro Yamaguchi, Tetsuo Nagano and Tsunehiko Higuhchi, J. Mol. Cat. A: Chemical, 219, 221-226 (2004).
  • "Recent Advances in the Design of Small Molecule-Based FRET Sensors for Cell Biology" Kazuya Kikuchi, Hideo Takakusa and Tetsuo Nagano, Trends in Analytical Chemistry, 23, 407-415 (2004).
  • "Rational Principles for Modulating Fluorescence Properties of Fluorescein" Tasuku Ueno, Yasuteru Urano, Ken-ichi Setsukinai, Hideo Takakusa, Hirotatsu Kojima, Kazuya Kikuchi, Kei Ohkubo, Shunichi Fukuzumi and Tetsuo Nagano, J. Am. Chem. Soc., 126, 14079-14085 (2004).
  • "Development of a Zinc Ion-Selective Luminescent Lanthanide Chemosensor for Biological Applications" Kenjiro Hanaoka, Kazuya Kikuchi, Hirotatsu Kojima, Yasuteru Urano and Tetsuo Nagano, J. Am. Chem. Soc., 126, 12470-12476 (2004).
  • "Synthesis and Fluorescent Properties of 2-(1H-Benzimidazol-2-yl)-phenol Derivatives" Jie Ouyang, Chenguang Ouyang, Yuki Fujii, Yoshiharu Nakano, Takuji Shoda and Tetsuo Nagano, J. Heterocyclic Chem., 41, 359-365 (2004).
  • "AMP-Activated Protein Kinase Inhibits Angiotensin II-Stimulated Vascular Smooth Muscle Cell Profiferation" Daisuke Nagata, Ryo Takeda, Masataka Sata, Hiroshi Satonaka, Etsu Suzuki, Tetsuo Nagano and Yasunobu Hirata, Circulation, 110, 444-451 (2004).
  • "Rational Design of Novel Photoinduced Electron Transfer Type Fluorescent Probes for Sodium Cation" Suguru Kenmoku, Yasuteru Urano, Koujirou Kanda, Hirotatsu Kojima, Kazuya Kikuchi and Tetsuo Nagano, Tetrahedron, 60, 11067-11073 (2004).
  • "Mitochondrial Signal Lacking Manganese Superoxide Dismutase Failed to Prevent Cell Death by Reoxygenation Following Hypoxia in a Human Pancreatic Cancer Cell Line, KP4V" Futoshi Hirai, Shigeatsu Motoori, Shizuko Kakinuma, Kazuo Tomita, Hiroko P. Indo, Hirotoshi Kato, Taketo Yamaguchi, Hsiu-Chuan Yen, Daret K. St.Clair, Tetsuo Nagano, Toshihiko Ozawa, Hiromitsu Saisho and Hideyuki J. Majima, Antioxidants & Redox Signaling, 6, 523-535 (2004).
  • "Modification of Intracellular Ca2+ Dynamics by Laser Inactivation of Inositol 1,4,5-Triphosphate Receptor Using Membrane-Permeant Probes" Takatoshi Yogo, Kazuya Kikuchi, Takanari Inoue, Kenzo Hirose, Masamitsu Iino and Tetsuo Nagano, Chemistry & Biology, 11, 1053-1058 (2004).
  • "Zinc Sensing for Cellular Application" Kazuya Kikuchi, Kensuke Komatsu and Tetsuo Nagano, Current Opinion in Chemical Biology, 8, 182-191 (2004).
  • "Determination of Origin of Ephedrine Used as Precursor for Illicit Methamphetamine by Carbon and Nitrogen Stable Isotope Ratio Analysis" Naoki Kurashima, Yukiko Makino, Setsuko Sekita, Yasuteru Urano and Tetsuo Nagano, Analytical Chemistry, 76, 4233-4236 (2004).
  • "A Novel Fluorescent Probe for Zinc Ion Based on BODIPY Chromophore" Hitomi Koutaka, Jun-ichi Kosuge, Noboru Fukasaku, Tomoya Hirano, Kazuya Kikuchi, Yasuteru Urano, Hirotatsu Kojima and Tetsuo Nagano, Chem. Pharm. Bull., 52, 700- 703 (2004).
  • "Distinct Glutamate Receptors Govern Differential Levels of Nitric Oxide Production in a Layer-Specific Manner in the Rat Cerebellar Cortex" Daisuke Okada, Chan-Choo Yap, Hirotatsu Kojima, Kazuya Kikuchi and Tetsuo Nagano, Neuroscience, 125, 461-472 (2004).
  • "Highly Sensitive Fluorescence Probes for Nitric Oxide Based on Boron Dipyrromethene Chromophore -Rational Design of Potentially Useful Bioimaging Fluorescence Probe-" Yu Gabe, Yasuteru Urano, Kazuya Kikuchi, Hirotatsu Kojima and Tetsuo Nagano, J. Am. Chem. Soc., 126, 3357- 3367 (2004).
  • "Characterization of N-methyl-d-aspartate Receptor Subunits Involved in Acute Ammonia Toxicity" Takahiro Kitano, Shinji Matsumura, Toshihito Seki, Takatoshi Hikida, Kenji Sakimura, Tetsuo Nagano, Masayoshi Mishina, Shigetada Nakanishi and Seiji Itoh, Neurochem. Int., 44, 83-90 (2004).
  • "活性酸素、一酸化窒素の蛍光プローブによる細胞可視化"　THE LUNG perspective, 小島宏建、浦野泰照、長野哲雄、12, 424-429 (2004).
  • "細胞機能を覗く可視化センサー分子のデザイン・合成・生物応用"　有機合成化学協会誌, 菊地和也、長野哲雄、62, 1006-1013 (2004).
  • "蛍光分光法" 蛋白質核酸酵素増刊号「バイオ高性能機器・新技術利用マニュアル」共立出版, Vol. 49, 1700-1706 (2004).
  • "生体可視化プローブの開発" 長野哲雄、学術月報, vol.57, No.3, 11-15 (2004)
  • "細胞内解析試薬"　長野哲雄、化学フロンティア ーナノバイオエンジニアリングー, 化学同人（杉本直己編）, 84-85 (2004).
  • "細胞を視てみよう　ーFRETって何ー"上野匡、長野哲雄、化学と薬学の教室, No.150, 10-13 (2004).
  • "生細胞内情報分子の蛍光可視化プローブ"　長野哲雄、「先端の分析法　ー理工学からナノ・バイオまでー」（株）エヌ・ティ－・エス, 2004年, 印刷中
  • "細胞を可視化する材料　ーバイオイメージングプローブの創製ー"長野哲雄、未来材料, （株）エヌ・ティ－・エス, pp.29ー35 (2004).
  • "創薬化学"　長野哲雄　編著、東京化学同人, 2004年
  • 薬学教科書シリーズ、"第8巻　医薬品の開発と生産"　長野哲雄（分担執筆）、東京化学同人, 2004年, 印刷中

ページトップへ戻る

2003年

  • "Active Oxygen Species Generated from Photoexcited Fullerene (C60) as Potential Medicines - O2-・ versus 1O2 -" Yoko Yamakoshi, Naoki Umezawa, Akemi Ryu, Kumi Arakane, Naoki Miyata, Yukihiro Goda, Toshiki Masumizu and Tetsuo Nagano, J. Am. Chem. Soc., 125, 12803-12809 (2003).
  • "Niric oxide (NO) Synthase mRNA Expression and NO Production via Muscarinic Acetylcholine Receptor-mediate Pathways in the CEM, Human Leukemic T-cell Line" Yuichiro Kamimura, Takeshi Fujii, Hirotatsu Kojima, Tetsuo Nagano and Koichiro Kawashima, Life Sciences, 72, 2151-2154 (2003).
  • "Rational Design Principle for Modulating Fluorescence Properties of Fluorescein-Based Probes by Photoinduced Electron Transfer" Tetsuo Miura, Yasuteru Urano, Kumi Tanaka, Tetsuo Nagano, Kei Ohkubo and Shunichi Fukuzumi, J. Am. Chem. Soc., 125, 8666-8671 (2003).
  • "Selective Detecting of Zinc Ions with Novel Luminescent Lanthanide Probes" Kenjiro Hanaoka, Kazuya Kikuchi, Hirotatsu Kojima, Yasuteru Urano and Tetsuo Nagano, Angewandte Chemie, Int. Ed., 42, 2996-2999 (2003) .
  • "Spatiotemporal Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptors Using Synthetic Small-Molecule Probes" Takanari Inoue, Kazuya Kikuchi, Kenzo Hirose, Masamitsu Iino and Tetsuo Nagano, Chemistry & Biology, 10, 503-509 (2003).
  • "Development of Selective, Visible Light-Excitable, Fluorescent Magnesium Probes with a Novel Fluorescence Switching Mechanism" Takuji Shoda, Kazuya Kikuchi, Hirotatsu Kojima, Yasuteru Urano, Hirokazu Komatsu, Koji Suzuki and Tetsuo Nagano, The Analyst, 128, 719-723 (2003).
  • "A Novel Design Method of Ratiometric Fluorescent Probes Based on Fluorescence Resonance Energy Transfer Switching by Spectral Overlap Integral" Hideo Takakusa, Kazuya Kikuchi, Yasuteru Urano, Hirotatsu Kojima and Tetsuo Nagano, Chemistry-A European Journal, 9, 1479-1485 (2003).
  • "Development of Novel Fluorescence Probes That Can Reliably Detect Reactive Oxygen Species and Distinguish Specific Species" Ken-ichi Setsukinai, Yasuteru Urano, Katsuko Kakinuma, Hideyuki J. Majima and Tetsuo Nagano, J. Biol. Chem., 278, 3170-3175 (2003).
  • "Attenuation of Neuropathic Pain by the Nociceptin/Orphanin FQ Antagonist JTC-801 is Mediated by Inhibition of Nitric Oxide Production" Tamaki Mabuchi, Shinji Matsumura, Emiko Okuda-Ashitaka, Takahiro Kitano, Hirotatsu Kojima, Tetsuo Nagano, Toshiaki Minami and Seiji Ito, Eur. J. Neurosci., 17, 1384-1392 (2003).
  • "Production of Singlet Oxygen on Irradiation of a Photodynamic Therapy Agent, Zinc-coproporphyrin III, with low host toxicity" Megumi Yamamoto, Tetsuo Nagano, Ichiro Okura, Kumi Arakane, Yasuteru Urano and Kazuhiko Matsumoto, Biometals, 16, 591-597 (2003).
  • "Light-Harvesting Ionic Dendrimer Porphyrins as New Photosensitizers for Photodynamic Therapy" Nobuhiro Nishiyama, Hendrik R. Stapert, Guo-Dong Zhang, Daisuke Takasu, Dong-Lin Jiang, Tetsuo Nagano, Takuzo Aida and Kazunori Kataoka, Bioconjugate Chemistry, 14, 58-66 (2003).
  • "細胞を視てみよう　ー蛍光物質はおもしろいー"上野　匡、長野哲雄、化学と薬学の教室, 149号, pp. 10-14 (2003).
  • "生体機能関連化学実験法"　長野哲雄、鈴木紀行、平野智也、水上進、瀬月内健一、高草英生、化学同人（日本化学会生体機能関連部会編）, pp.113-125
  • "光誘起電子移動理論に基づく蛍光プローブの精密設計"　浦野泰照、長野哲雄、ぶんせき, No.8, 426-432 (2003)
  • “有機化学者のチャレンジ：本物を目指して”長野哲雄、小田嶋和徳、藤井信孝、西田篤司、ファルマシア, 39, 13-18（2003).
  • "細胞を視てみようーバイオイメージングとはー"長野哲雄、化学と薬学の教室, 148号, No381, pp.12ー15 (2003).
  • "活性酸素イメージングプローブ"　長野哲雄、瀬月内健一、浦野泰照、実験医学, Vol.21, No.15, 2144-2146 (2003).
  • “有機化学者のチャレンジ：本物を目指して”長野哲雄、小田嶋和徳、藤井信孝、西田篤司、ファルマシア, 39, 13-18（2003）

ページトップへ戻る

2002年

  • "Design and Synthesis of a Novel Magnetic Resonance Imaging Contrast Agent for Selective Sensing of Zinc Ion" Kenjiro Hanaoka, Kazuya Kikuchi, Yasuteru Urano, Michiko Narazaki, Takashi Yokawa, Shigeru Sakamoto, Kentaro Yamaguchi and Tetsuo Nagano, Chemistry & Biology, 9, 1027-1032(2002).
  • "A Novel, Cell-Permeable, Fluorescent Probe for Ratiometric Imaging of Zinc Ion" S. Maruyama, K. Kikuchi, T. Hirano, Y. Urano and T. Nagano, J. Am. Chem. Soc., 124, 10650-10651(2002).
  • "Multiple Active Intermediates in Oxidation Reaction Catalyzed by Synthetic Heme-thiolate Complex Relevant to Cytochrome P450" Noriyuki Suzuki, Tsunehiko Higuchi and Tetsuo Nagano, J. Am. Chem. Soc., 124, 9622-9628 (2002).
  • "Mossy Fiber Zn2+ Spillover Modulates Heterosynaptic N-methyl-D-aspartate Receptor Activity in Hippocampel CA3 Circuits" Sayaka Ueno, Masako Tsukamoto, Tomoya Hirano, Kazuya Kikuchi, Maki K. Yamada, Nobuyoshi Nishiyama, Tetsuo Nagano, Norio Matsuki and Yuji Ikegaya, J. Cell Biology, 158, 215-220 (2002).
  • "Improved Fluorescent Probes for Zinc, ZnAFs, Suitable for Biological Applications." Tomoya Hirano, Kazuya Kikuchi, Yasuteru Urano and Tetsuo Nagano, J. Am. Chem. Soc., 124, 6555-6562 (2002).
  • "A Fluorescent Anion Sensor That Works in Neutral Aqueous Solution for Bioanalytical Application" Shin Mizukami, Tetsuo Nagano, Yasuteru Urano, Akira Odani and Kazuya Kikuchi, J. Am. Chem. Soc.,124, 3920-3925 (2002).
  • "Hydrophobic Modifications at 1-Phosphate of Inositol 1,4,5-Trisphosphate Analogues Enhance Receptor Binding" Waka Nakanishi, Kazuya Kikuchi, Takanari Inoue, Kenzo Hirose, Masamitsu Iino and Tetsuo Nagano,Bioorganic & Medicinal Chemistry Letters, 12, 911-913 (2002).
  • "Orthogonality of Calcium Concentration and Ability of 4,5-Diaminofluorescein (DAF-2) to Detect NO" Noriyuki Suzuki, Hirotatsu Kojima, Yasuteru Urano, Kazuya Kikuchi, Yasunobu Hirata and Tetsuo Nagano, J. Biol. Chem., 277, 47-49 (2002).
  • "Design and Synthesis of an Enzyme-Cleavable Sensor Molecule for Phosphodiesterase Activity Based on Fluorescence Resonance Energy Transfer" Hideo Takakusa, Kazuya Kikuchi, Yasuteru Urano, Shigeru Sakamoto, Kentaro Yamaguchi and Tetsuo Nagano, J. Am. Chem. Soc., 124, 1653-1657 (2002).
  • "Bioimaging of Nitric Oxide" Tetsuo Nagano and Tetsuhiko Yoshimura, Chemical Reviews, 102, 1235-1269 (2002).
  • "Gi and Go as a Redox Sensor" Motohiro Nishida, Kevin L. Schey, Shuichi Takagahara, Kenji Kontani, Toshiaki Katada,Yasuteru Urano, Tetsuo Nagano, Taku Nagao and Hitoshi Kurose, J. Biol. Chem., 277, 9036-9042(2002).
  • "Impurity Profiling of Ephedrines in Methamphetamine by High-Performance Liquid Chromatography" Yukiko Makino, Yasuteru Urano and Tetsuo Nagano, J. Chromatography A, 947, 151-154 (2002).
  • "Pregnenolone Sulfate Acutely Enhances NO Production in the Rat Hippocampus: Digital Fluorescence Study Using NO Reactive Dye" Norio Takata, Keisuke Shibuya, Masashi Okabe, Tetsuo Nagano, Hirotatsu Kojima, Suguru Kawato, Bioimages, 10, 1-8 (2002).
  • "PET理論と蛍光プローブ"　浦野泰照、長野哲雄、現代化学, 12月号, No381, pp.44ー50 (2002).
  • "FRET型合成小分子プローブの分子設計"　高草英生、菊地和也、長野哲雄、現代化学, 10月号, No379, pp.22-27 (2002).
  • "Cosmeceuticalに期待すること　ー生命科学研究の動向から探るー"　長野哲雄、日本香粧品科学会誌, 26, 152-153 (2002)

ページトップへ戻る

2001年

  • "Selective Sensing of Zinc Ion with a Novel Magnetic Resonance Imaging Contrast Agent" Kenjiro Hanaoka, Kazuya Kikuchi, Yasuteru Urano and Tetsuo Nagano, J. Chem. Soc., Perkin Transaction 2, 1840-1843 (2001).
  • "Rational Design of Fluorescein-Based Fluorescence Probes. -Mechanism-Based Design of a Maximum Fluorescence Probe for Singlet Oxygen-" Kumi Tanaka, Tetsuo Miura, Naoki Umezawa, Yasuteru Urano, Kazuya Kikuchi, Tsunehiko Higuchi and Tetsuo Nagano, J. Am. Chem. Soc.,123, 2530-2536 (2001).
  • "Small Molecule-Based Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptor" Takanari Inoue, Kazuya Kikuchi, Kenzo Hirose, Masamitsu Iino and Tetsuo Nagano, Chemistry & Biology, 8, 9-15 (2001).
  • "Intramolecular Fluorescence Resonance Energy Transfer System with Coumarin Donor Included in beta-Cyclodextrin" Hideo Takakusa, Kazuya Kikuchi, Yasuturu Urano, Tsunehiko Higuchi and Tetsuo Nagano, Analytical Chemistry, 73, 939-942 (2001).
  • "Bioimaging of Nitric Oxide with Fluorescent Indicators Based on Rhodamine Chromophore" Hirotatsu Kojima, Miki Hirotani, Naoki Nakatsubo, Kazuya Kikuchi, Yasuteru Urano, Tsunehiko Higuchi, Yasunobu Hirata and Tetsuo Nagano, Analytical Chemistry, 73, 1967-1973 (2001).
  • "Visualization of Oxygen Concentration-Dependent Production of Nitric Oxide in Rat Hippocampal Slices during Aglycemia" Hirotatsu Kojima, Mihoko Hirata, Yoshihisa Kudo, Kazuya Kikuchi and Tetsuo Nagano, J. Neurochem., 76, 1404-1410 (2001).
  • "Overexpression of Mitochondrial Manganese Superoxide Dismutase Protects Against Radiation-Induced Cell Death in Human Hepatocellular Carcinoma Cell Line, HLE" Shigeatsu Motoori, Hideyuki J. Majima, Masaaki Ebara, Hirotoshi Kato, Futoshi Hirai, Shizuko Kakinuma, Chizuru Yamaguchi, Toshihiko Ozawa, Tetsuo Nagano, Hirohiko Tsujii and Hiromitsu Saisho, Cancer Research 61, 5382-5388 (2001).
  • "Selective Inhibition of Human Inducible Nitric Oxide Synthase by S-alkyl-L-isothiocitrulline-Containing Dipeptides" Jung-Min Park, Tsunehiko Higuchi, Kazuya Kikuchi, Yasuteru Urano, Hiroyuki Hori, Takeshi Nishino, Junken Aoki, Keizo Inoue and Tetsuo Nagano, British Journal of Pharmacology, 132, 1876-1881 (2001).
  • "Synthesis of 5,10,15,20-Tetrakis(4-tert-butyl-2,6-dicarboxyphenyl)porphyrin: A Versatile Bis-Faced Porphyrin Synthon for D4-symmetric Chiral Porphyrin" Hiroshi Nakagawa, Tetsuo Nagano and Tsunehiko Higuchi, Organic Letters, 3, 1805-1807 (2001).
  • "Synthesis and Optical Properties of a New Class of Pyrromethene-BF complex Fused with Rigid Bicycle Rings and Benzo Derivatives" Mitsuo Wada, Satoshi Ito, Hidemitsu Uno, Takashi Murashima, Noboru Ono, Toshiyuki Urano and Yasuteru Urano, Tetrahedron Letters 42, 6711-6713 (2001).
  • "高感度一重項酸素蛍光プローブの開発"　浦野泰照、長野哲雄、医学のあゆみ, 別冊 "酸化ストレス" pp. 131-134 (2001)
  • "バイオイメージングのための新規Zn2+蛍光プローブ" 菊地和也、平野智也、長野哲雄、化学と生物, 39, 549-553 (2001)

ページトップへ戻る